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Symbol
Name
ID
Sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
MGI:1344402
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal splenocyte proliferation
increased susceptibility to induced colitis
abnormal dendritic cell physiology
abnormal chemokine secretion
abnormal interleukin secretion
increased interleukin-6 secretion
increased susceptibility to endotoxin shock
increased inflammatory response
Availability Mouse Genotype
Sigirrtm1Lix/Sigirrtm1Lix
Sigirrtm1Mant/Sigirrtm1Mant *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory