Symbol Name ID |
Sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain MGI:1344402 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
abnormal splenocyte proliferation |
increased susceptibility to induced colitis |
abnormal dendritic cell physiology |
abnormal chemokine secretion |
abnormal interleukin secretion |
increased interleukin-6 secretion |
increased susceptibility to endotoxin shock |
increased inflammatory response |
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Availability | Mouse Genotype | |||||||||
Sigirrtm1Lix/Sigirrtm1Lix | ||||||||||
Sigirrtm1Mant/Sigirrtm1Mant | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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